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Wegovy is the only option of these three that has specifically been approved for use as a weight loss medication, only really differing from Ozempic by its recommended dosages
For example, evodiamine has been found to inhibit histone lactylation at the HIF-1 promoter, suppressing angiogenesis and programmed death-ligand 1 expression while inducing ferroptosis in prostate cancer cells (122)
Other controlled weight loss drugs (older amphetamines, Schedule II stimulants) face stricter scrutiny
Great post, Stuart Phillips
If your denial is appealable, request a Letter of Medical Necessity from your prescriber
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